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Experts suspect that gender differences in mortality patterns may be influenced at least in part by sex hormones, namely the male hormone testosterone and the female hormone estrogen. The conspicuous peak in the sex-mortality ratio at puberty, for example, coincides with increased testosterone production in men. Because the male hormone has been linked with aggression and competitiveness as well as libido, some researchers ascribe this spike in male mortality to “testosterone toxicity.” {{Later in life, testosterone puts men at risk biologically}} as well as behaviorally. It increases blood levels of the bad cholesterol (known as LDL, for low-density lipoprotein) and decreases levels of the good one (HDL, for high-density lipoprotein), putting men at greater risk of heart disease and stroke.

{{It is well known that Women Live Longer than Men.}}

Other effects of androgens on the long run :

– Candida Overgrowth, Candida albicans, yeast infections
– liver intoxication and destruction
– skin infections, acne, oily skin, nail infections
– shrinkage of hair follicles, hair loss
– urination disorders and irritable bladder, prostatis, enlarged prostate
– hirsutism
– osteoporosis
– Breast cysts
– rosacea
– cancer
– inflammation
– headaches
– diarrhea
– diabetes
– hypertension
– neural and vascular damage, Alzheimer’s disease
– heart disease and stroke
– aging in general

Estrogen, on the other hand, has beneficial effects on cardiovascular health, lowering LDL cholesterol and increasing HDL cholesterol. A recent study at the University of Washington suggests that estrogen may exert these effects by regulating the activity of liver enzymes involved in cholesterol metabolism.

Now the interesting question is : how to put a stop to androgens and how to promote estrogens ?

Here is an extensive list of herbs and food that can help for that and to increase life span (antifungals and androgen reducing are linked) :

– green tea : 60% reduction of sebum after 8 weeks using a formulation containing 3% green tea extract
– sage leaf : sage reduce sebum, is antifungal. Inhibit gonadotrophic or prolactin They found that each oil turned on estrogen-regulated genes and inhibited an androgen-regulated gene. Have an anti-androgenic or sebum-reducing ; is anti-fungal, antiseptic and astringent
– curcumin (turmeric) root : Antimicrobial, antifungal ; have an anti-androgenic or sebum-reducing effect
-fennel seed : having strong estrogenic effects ; Antifungal
– cinnamon bark : antimicrobial/Antifungal ; lower blood sugar levels and reduces serum insulin levels ; significant improvement in growth hormone activation within the fibroblasts
– pygeum leaf : antiseptic, contains natural sterols and fatty acids ; have an anti-androgenic or sebum-reducing effect ; cleanse and regenerate the liver ; contains an antiandrogenic compound atraric acid ; the highest antiandrogenic effect ; has a well known antiandrogenic effect by binding to the androgen receptor and shows effective results in treating BPH and consistent and significant reduction of DHT ; Phytoestrogenic herbs lower testosterone by increasing estrogen and anti-5 alpha reductase
– saw palmetto fruit : saw palmetto is antiseptic, antifungal ; contains natural sterols and fatty acids ; decrease DHT ; Has anti-androgenic effects lowering the production of male hormones including excess hair growth ; treat bladder and prostate conditions ; prostate support ; prevent testosterone from converting into DHT by inhibiting the enzyme that is responsible for this process ; can give you fuller hair and a clearer skin, because DHT is associated with hair loss and acne ; reduce 5 alpha reductase
– borage oil : The gamma-linoleic acid found in borage oil can help to dilute sebum or oil, secreted by the sebaceous glands.
So using borage or evening primrose oil in OCM might reduce sebum production.
– damiana leaf
– nettle root : Traditionally, nettle root has been used as an enhancer of healthy urinary flow and as an astringent. Used as an enhancer of healthy urinary flow and as an astringent ; have an anti-androgenic or sebum-reducing effect ; contains a protein molecule called UDA which attacks fungus in the body. (Great for candida sufferers) Nettle blocks lactic acid cycle which starves cancer cells ; is used as an antifungal for urination disorders and irritable bladder ; decrease DHT ; stimulate prolactin production in the body.  These herbs are most commonly used to prevent testosterone from converting into DHT by inhibiting the enzyme that is responsible for this process
– kudzu root : plant from China and Japan. Rich in flavonoids, removes redness, flaking and tightness of the skin. Inhibits the activity of phospholipase PLA2, ensures protective effect on sensitive skin, softens skin lesions caused by rosacea. Kudzu contains the isoflavone daidzein which has anti-inflammatory, antimicrobial and anticancer (related to genistein, it is anti ñ leukemic; namely acts against leukaemia) agent. Kudzu root contains: Phytoestrogens including the isoflavonoids genistein, daidzein, formononetin and biochanin-A. Kudzu root is also rich in isoflavone glycosides, such as daidzein and puerarin. Depending on its growing conditions, the total isoflavone content varies from 1.77 – 12.0%, with puerarin in the highest concentration, followed by daidzin and daidzein. Kudzu also contains many other flavonoid-type antioxidants and is rich in protein (10).
Kudzu root’s compounds can affect neurotransmitters including serotonin, GABA and glutamate. Kudzu’s mechanism perhaps includes brain reward pathways and alcohol metabolism. Kudzu contains the isoflavone daidzein which has anti-inflammatory, antimicrobial and anticancer (related to genistein, it is anti – leukemic; namely acts against leukaemia) agent. It is also a unique source of the isoflavone puerarin. Kudzu has been also used against cluster headaches, migraine, allergies, diarrhea and for the control of some postmenopausal symptoms. It is also studied for Alzheimer’s disease. It may help at diabetes, cardiovascular disease and hypertension (1).
Kudzu has been studied, as a herb, against alcoholism. It traditionally has been used in China against alcoholism and hangover. Its root has been used traditionally to prevent excessive alcohol consumption, while its flower has been used traditionally to detoxify the liver and alleviate the symptoms of alcoholism (1).
– red clover
– lavender oil : DHT was inhibited in a concentration-dependent manner by both lavender oil and tea tree oil ; lavender oil is a powerful antifungal agent that fights and prevents skin and nail infections, including Candida albicans. Transactivation of the MMTV-luciferase reporter plasmid by 0.1 nM DHT was inhibited in a concentration-dependent manner by both lavender oil and tea tree oil.
– tea tree oil
– ginkgo biloba leaf
– fenugreek seed
– flax seed
– lupin seed : Lupin proteins inhibit the 5-a reductase’s action thus reducing the quantity or the produced DHT which causes the shrinkage of hair follicles (in vitro studies).
– lentils
– beans
– carrots root
– sun flower seed
– soybean : We have demonstrated the inhibitory activity of [soy] isoflavone . . . suggesting that genistein and isoflavone would be used as an effective agent for androgenetic acne and for the inhibition of secretion of sebum by modifying androgen conversion.
– tomato extract : Lycopene possesses antibacterial and antifungal properties ; tomato contains lycopene, quercetin (lowering DHT)
– pumpkin seed : contains a lot of zinc. Zinc displays ‘in vitro’ some antiandrogen activity through an inhibition of the 5 alpha-reductase activity. The oil fraction of pumpkin seed has been shown to inhibit 5 alpha-reductase. The mixture of delta 7-sterols has been shown to inhibit the binding of DHT to androgen receptors.
– peanut
– grapefruit
– wild yam root
– motherwort
– spearmint, mint : inhibit gonadotrophic or prolactin secretion ; antimicrobial ; testosterone 5 .ALPHA.-reductase inhibition
– Milk Thistle : Milk thistle and pygeum africanum have been studied for their ability to cleanse and regenerate the liver.
– melilot
– cherry stem
– Hieracium pilosella
– lime sapwood
– Chamomile
– olive oil
– goji fruit
– cumin seed
– cardamom : cardamom inhibit the growth of viruses, bacteria, fungus, and mold
– bresil nut
– feta cheese
– rice
– blueberry fruit
– sesame seed
– pineapple fruit
– Fraxinus infusion
– thym leaf : inhibit gonadotrophic or prolactin They found that each oil turned on estrogen-regulated genes and inhibited an androgen-regulated gene. bone growth ; inhibit gonadotrophic or prolactin ; turned on estrogen-regulated genes and inhibited an androgen-regulated gene ; having strong estrogenic effects ; help to open the pores of hair follicles and nourish hair roots and damaged hair ; Antimicrobial ; have an anti-androgenic or sebum-reducing effect
– licorice :  Licorice root extract has inhibitory actions of testosterone 5-alpha-reductance, lipase and phospholipase A2, as well as androgen receptors antagonist that diminish sebum output. Among the herbal extracts tested, polyol-soluble licorice extract P-U (product name) derived from Glycyrrhiza inflata showed the most potent testosterone 5 .ALPHA.-reductase inhibition, androgen receptor binding inhibition and antimicrobial activities, which are closely related to sebum secretion. In addition to the findings on polyol-soluble licorice extract P-U, clove extract and peppermint extract showed testosterone 5 .ALPHA.-reductase inhibition, arnica extract and rose fruit extract showed androgen receptor binding inhibition.
– brewer yeast
– propolis : Propolis has strong anti-fungal, anti-inflammation and anti-protozoan effect and has been proven effective in cases of STDs like trich and candida.
– green bean
– glutamate monosodium (1 pinch per meal)
– black pepper seed
– garlic
– coriander seed
– seaweed (chlorella, spirulina, kelp) : The findings taken together suggest that SOZC can significantly ameliorate symptoms of acne vulgaris, particularly in terms of reducing sebum production and populations of Propionibacterium acnes.
– cappers
– apple cider vinegar : apple cider vinegar has antibacterial and antifungal properties to help prevent acne and skin infections.
– citrus fruit
– bread
– water
– bee pollen : Bee pollen for candida seems to be a strange combination however bee pollen is actually a natural treatment option for this unpleasant condition.
– date fruit
– buckwheat
– red wine (1 glass drink per day)
– blackcurrant
– anise seed
– chickpea
– bamboo shoot
– red vine leaf
– grape seed
– shiitake and maitake mushroom
– maca root
– Ginger root : Ginger has strong antibacterial and some antifungal properties, which can aid in the treatment of yeast infections.
– Aloe vera juice
– Burdock root
– eucalyptus leaf : antifungal

Pennyroyal, sage, marjoram, thyme, rosemary, and hyssop inhibit gonadotrophic or prolactin They found that each oil turned on estrogen-regulated genes and inhibited an androgen-regulated gene.

Zava, PhD also identifies Bloodroot, Ocotillo, Mandrake, Oregano, Damiana, Pennyroyal, Verbenna, Nutmeg, Tumeric, Yucca, Thyme, Calamus rt., Red Clover, Goldenseal, Licorice, Mistletoe, Cumin, Fennel, Camomille, Cloves as having strong estrogenic effects.

Tanins have been demonstarted to have a powerful anti-fungal and astringent action in a multitude of clinical studies.

Antimicrobial herbs also refered to as: antibiotic, anti-infectives or antiseptic herbs :

   Aloe (Aloe vera)
   Aniseed (Pimpinella anisum)
   Astragalus (Astragalus membranaceus)
   Barberry (Berberis vulgaris)
   Buchu ( Agathosma betulina)
   Burdock (Arctium lappa)
   Calendula (Calendula officinalis)
   Caraway (Carum carvi) oil
   Cayenne (Capsicum annuum)
   Chamomile (Matricaria recutita)
   Cloves (Syzygium aromaticum
   Coriander (Coriandrum sativum)
   Coriolus (Coriolus versicolor)
   Cranberry (Vaccinium macrocarpon)
   Echinacea (Echinacea angustifolia)
   Elecampane (Inula helenium)
   Feverfew (Tanacetum parthenium)
   Garlic (Allium sativum)
   Gentiana (Gentiana lutea)
   Ginger (Zingiber officinale)
   Goldenseal (Hydrastis canadensis)
   Gymnema (Gymnema sylvestra)
   Juniper (Juniperus communis)
   Licorice (Glycyrrhiza glabra)
   Marigold (Tagetes)
   Marjoram (Origanum majorana)
   Meadowsweet (Filipendula ulmaria)
   Myrrh (Commiphora myrrha)
   Olive (Olea europaea)
   Oregano (Origanum vulgare)
   Pau d’Arco (Tabebuia avellanedae)
   Peppermint (Mentha piperita)
   Pygeum (Prunus africana)
   Rosemary (Rosmarinus officinalis)
   Sage (Salvia officinalis)
   Saw Palmetto (Serenoa repens)
   Tea Tree Oil (Melaleuca alternifolia)
   Thuja (Thuja occidentalis)
   Thyme (Thymus vulgaris)
   Turmeric (Curcuma longa)
   Uva Ursi (Arctostaphylos Uva Ursi)
   Wormwood (Artemisia absinthium)

Malassezia yeasts secrete an enzyme called phospholipase A2, which liberates a chain of inflammatory cytokines. So, this is why anti-fungals help reduce hair loss

As far as the sebum itself, too much IGF-1 increases sebum production. Malassezia yeasts secrete an enzyme called phospholipase A2, which liberates a chain of inflammatory cytokines. So, this is why anti-fungals help reduce hair loss.

Phospholipase-A2-Inhibitor : Betulinic-Acid : Grape

B6 in tandem with the mineral Zinc is known to combat the overproduction of DHT form testosterone that weaken hair follicles and cause premature baldness in men.

As most naturopathic physicians would agree, prostatitis is not caused by bacteria in the prostate but most frequently due to fungus, like Candida, in the prostate…